Cutaneous Blastomycosis Masquerading as Pyoderma Gangrenosum

Cutaneous blastomycosis masquerading as pyoderma gangrenosum.

Cutaneous blastomycosis (CB) is associated with a variety of skin manifestations. Among other entities, CB may be mistaken for pyoderma gangrenosum due to overlap of findings on histopathologic examination. We report a case of CB, initially diagnosed as pyoderma gangrenosum and treated with steroids, leading to disseminated blastomycosis and acute respiratory distress syndrome (ARDS).

CD8-positive Mycosis Fungoides Masquerading as Pyoderma Gangrenosum

Mycosis fungoides (MF), a primary cutaneous T-cell lymphoma, accounts for <1% of non-Hodgkin lymphomas. The diagnosis of classic MF is based on a constellation of typical clinical presentation, histopathology, immunohistochemistry, and T-cell monoclonality detected by molecular studies. Rarely, atypical clinical presentation may occur. The typical immunohistochemical phenotype is, CD2 +ve, CD3 ...

Cutaneous Pyoderma Gangrenosum of the Hand

Pyoderma gangrenosum-like primary cutaneous cryptococcosis.

Sir, The first published case of a Cryptococcus infection was reported by Zenker in 1861 (1), when he described a case of a man dying from a fungal infection involving the central nervous system (CNS). Thereafter, reports of Cryptococcus infections increased significantly. Today most cases occur in immunocompromised, often HIVinfected, individuals (2). C. neoformans (CN) is a ubiquitous yeast-l...

Pyoderma gangrenosum.

Pyoderma gangrenosum (PG) is an idiopathic, ulcerative, noninfective chronic inflammatory skin disorder of unknown etiology. It is associated with systemic medical illness in 50% of cases like inflammatory bowel disease, systemic arthritis, haematological diseases and malignancies. Characteristic lesions begin as pustule or vesiculopustule and progresses to an ulcer or deep erosion with violace...